Ready-to-use DNA constructs engineered for complex replication, transcription, chromatin, and repair studies.
Mission
Single-molecule biophysics is entering a new era, shifting from basic model systems to the visualization of complex, multi-protein mechanisms. We handle the biochemical engineering so your lab can immediately step onto this new frontier. By bypassing weeks of DNA troubleshooting, you accelerate discoveries in high-priority fields like real-time DNA repair, replication, chromatin, and transcription regulation. Reclaim your time, trust your DNA tethers, and push the boundaries of knowledge from day one.
PARP1, APE1, XRCC1, Pol β, FEN1, LIG1/LIG3, EXO1, DNA2, MRE11–RAD50–NBS1, RPA, RAD51, RAD52, BRCA2, RAD54, ATR–ATRIP, 9-1-1
RFC, PCNA, Pol δ, Pol ε, CMG complex, BLM, WRN, PIF1
RNA polymerase tracking, transcription factors, nucleosome positioning, chromatin remodelers
DNA/RNA hairpins, G-quadruplexes, FRET spectroscopy, protein folding pathways, multi-fragment binding affinity comparison
Our constructs cost less than the time you would spend building and validating them yourself. When the catalog falls short, we collaborate to develop exactly what your experiment requires.
What we serve